Depends on what you consider "sadness" and "crushing despair."

[She responds a little flatly, though she can tell that it's obviously a joke. For a moment she pauses, considering, and then goes on.]

For me, "sadness" is the canned meat that tastes like the cow it came from has been dead for over half a century. "Despair" on the other hand is the spinach, which I suspect has some rad exposure.